111Skin Wrinkle Erasing Retinol Patches in Beauty: NA. 111Skin Wrinkle Erasing Retinol Patches in Beauty: NA. Developed by Dr Yannis Alexandrides to tackle deep expression lines overnight, the revolutionary Wrinkle Erasing Retinol Patches precisely target expression lines through innovative microcone technology that is clinically proven to give 2x the absorption speed and depth of active ingredients than topical skincare. The tiny needle-like patches dissolve upon contact with skin's moisture to deliver a potent blend of Retinol, Vitamin C and a powerful Peptide complex. A needle-free fix for fine lines and wrinkles that helps improve expression lines overnight. Helps skin elasticity and plumpness increase while providing skin with a smoother texture.. Active ingredients: Retinol Sodium Hyaluronate/Hyaluronic Acid Ascorbyl Glucoside. 3 sets. Each set includes: 2 x semi-circle patches for targeting crow's feet or nasolabial folds 2 x strips for targeting forehead expression lines 1 x patch for targeting frown lines. Step 1: Remove the film from both sides of the patches with dry hands and place them onto clean, dry, makeup-free skin.. Step 2: Gently pat each patch into place and proceed with your regular skincare routine, ensuring no product touches the patches.. Step 3: Leave on for at least two hours, but ideally overnight. Remove before your AM routine and always apply SPF after use.. 111R-WU112. INRMRMS01. Working in collaboration with space scientists responsible for the well-being of astronauts, renowned cosmetic surgeon Dr. Yannis Alexandrides developed the patented NAC Y2 formula that runs through the core of his highly effective skincare line. Named after his Harley Street, London clinic, 111SKIN's cutting-edge products feature potent healing ingredients designed to promote a youthful and radiant appearance while offering unprecedented protection against environmental damage.