What is it: A super-size duo from Dr. Denese with an effective formulation of amino acid peptides that helps address the appearance of deep, defined lines and wrinkles, and helps soften the appearance of expression lines on the face and neck. With this Auto-Delivery plan, you'll receive a new duo approximately every four months for one year. A one-time standard shipping and handling fee will be applied to your first shipment only. Who is it for: Anyone who has deep, visible defined lines and wrinkles; facial expression lines; lack of firmness to the skin; or dry, dehydrated skin on the neck and chest area. Why is it different: Formulated with Pro-Peptide Factor, this duo helps to address the appearance of deep, defined lines and wrinkles on the face and neck area. You can add Triple Strength Wrinkle Smoother Advanced Treatment to whatever you are using on a daily basis. The Triple Strength Neck Wrinkle Smoother also helps to firm and hydrate the neck and decollete, giving it a more youthful-looking appearance. How do I use it: After nighttime cleansing, Firming Facial Pads (not included), and any serums, apply Triple Strength Wrinkle Smoother Advanced Treatment to your entire face. Apply Triple Strength Neck Wrinkle Smoother in an upward motion to the entire neck and decollete area every morning and evening. From Dr. Denese.