Pick up this pair of Perricone MD Facial Creams in both a day and nighttime formula. And with this Auto-Delivery plan, receive a new shipment approximately every six months for three years. Neuropeptide Facial Cream helps to address the appearance of skin texture, the loss of elasticity, and leaves skin looking youthful and glowing. Neuropeptide Night Cream helps address the appearance of wrinkles, helps hydrate skin, softens skin's texture, and helps reduce the look of dry lines. How do I use it: In the morning, apply the Neuropeptide Facial Cream onto targeted areas of a cleansed face, focusing on the contours of the cheeks, forehead and jawline. Neuropeptide Night Cream should always be your last product before you apply a moisturizer. You only need a dime-size amount, because it's heavily concentrated. Massage it into the skin to activate it. Apply it up under the chin and jawline. Continue to massage it up behind the ears and around the eye area. From Perricone MD.